CryoLife, Inc. Announces First Shipment of BG3000 Pre-filled BioGlue Surgical Adhesive Delivery System

ATLANTA--(BUSINESS WIRE)--April 5, 1999--CryoLife, Inc. (NYSE:CRY), the leader in the development and commercialization of implantable living human tissues and a manufacturer and distributor of stentless heart valves and surgical adhesives, announced today that the first shipment into the European Union of the Company's new pre-filled BioGlue(R) surgical adhesive delivery system, BG3000, was made in late March. In mid-February, the Company received "CE" (product certification) mark approval for the distribution of the new delivery system in European markets. Since the initial shipment of BioGlue surgical adhesive approximately one year ago, total BioGlue surgical adhesive revenues have been $1.15 million, including this shipment of the BG3000. The new delivery system provides surgeons with a pre-filled, ready-to-use delivery device for the use of BioGlue surgical adhesive in the operating room. BioGlue surgical adhesive is "CE" marked for vascular and pulmonary repair applications.

Steven G. Anderson, President and Chief Executive Officer of CryoLife, Inc., said, "We are pleased to be announcing this first shipment of the newly enhanced delivery system for BioGlue surgical adhesive. This shipment was also the first shipment of BioGlue manufactured in our recently expanded manufacturing facilities. To my knowledge, BioGlue is now the only commercially available surgical adhesive in the world that does not require significant preparation time in the operating room. It is stored at room temperature and is ready to use the minute it is removed from the package."

Founded in 1984, CryoLife, Inc. is the leader in the development and commercialization of implantable living human tissues for use in cardiovascular, vascular, and orthopaedic surgeries throughout the United States and Canada. The Company's BioGlue(R) surgical adhesive, CE marked in the European Union for use in vascular and pulmonary sealing and repair, is distributed throughout Europe. The Company also manufactures CryoLife-O'Brien(R) and CryoLife-Ross(TM) stentless porcine heart valves which are distributed within the European Community.

Editor's Note:
CryoLife Customer Service may be accessed by telephone:
1-800-438-8285 (U.S. and Canada)
1-770-419-3355 (International)
1-770-590-3753 (International fax)
E-mail: For additional information about the Company,
        visit CryoLife's web site:
        http://www.cryolife.com


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     CONTACT: CryoLife Inc., Atlanta
              Roy Vogeltanz, 800/438-8285